Program

Registration: Anasazi Ballroom
Talks: Anasazi Ballroom
Poster session: El Dorado A
Breakfast, Receptions, Lunch and Dinner: El Dorado B


Saturday, May 13, 2017
1:00 – 5:00 pmRegistration
5:00 – 5:10 pmWelcome and Opening Remarks
Opening SessionChair: David Eisenberg, UCLA
5:10 – 5:45 pmTom Terwilliger, LANL
"Model-building using cryo-EM and crystallographic maps"
5:45 – 6:20 pmHao Wu, Harvard Medical School
"Structures of Supramolecular Signaling Complexes"
6:20 – 6:30 pmShort Break
6:30 – 7:15 pmEvening Lecture
Chair: Natalie Strynadka, University of British Columbia
Speaker: Michael Rossmann, Purdue University
"The structure of the immature, mature and neutralized Zika Virus"
7:15 – 8:45 pmReception and Dinner
8:45 – 10:00 pmDrinks and Mixing

Sunday, May 14, 2017
7:00 – 8:30 amBreakfast
Session IMembrane Proteins
Chair: Hao Wu, Harvard Medical School
8:30 – 9:15 amWayne Hendrickson, Columbia University
9:15 – 9:45 amSusan Buchanan, National Institutes of Health
9:45 – 10:05 amRefreshments & Break
10:05 – 10:45 amRobert Stroud, University of California, San Francisco
"The mechanism of Voltage and nutrient regulation, and inhibition of an endolysosomal ion channel; a cure for Ebola"
10:45 – 11:20 amNieng Yan, Tsinghua University
11:20 – 11:55 amNatalie Strynadka, University of British Columbia
12:00 – 1:00 pmLunch
Session IINucleic Acid and Protein-Nucleic acid Complexes
Chair: Tom Steitz, Yale University
1:00 – 1:40 pmJody Puglisi, Stanford University
1:40 – 2:10 pmCi Ji Lim, University of Colorado, Boulder
2:10 – 2:30 pmRefreshments & Break
2:30 – 3:10 pmShigeyuki Yokoyama, RIKEN
3:10 – 3:50 pmJamie Cate, University of California, Berkeley
"Structural basis for regulation of human translation"
3:50 – 4:30 pmLeemor Joshua-Tor, Cold Spring Harbor Laboratory
4:30 – 6:30 pmPoster Session with Drinks & hors d'oeuvres
6:30 – 7:15 pmEvening Lecture:
Chair: Jamie Cate, University of California, Berkeley
Speaker: Eva Nogales, University of California, Berkeley
"Microtubule Structure, Dynamics and Interactions"
7:15 – 8:45 pmDinner
8:45 – 10:00 pmDrinks and Mixing

Monday, May 15, 2017
7:00 – 8:30 amBreakfast
Session IIIDisease and Drug Discovery
Chair: Dorothee Kern, Brandeis University
8:30 – 9:15 amErica Ollmann Saphire, The Scripps Research Institute
"The Lassa virus glycoprotein: It takes a village"
9:15 – 9:45 amElizabeth Goldsmith, UT Southwestern Medical Center
9:45 – 10:15 amCatherine Drennan, Massachusetts Institute of Technology
"Shake, Rattle, & Roll: Capturing Snapshots of Metalloproteins in Action"
10:15 – 10:35 amRefreshments & Break
10:35 – 11:20 amIan Wilson, The Scripps Research Institute
"Structure-based design of vaccines and therapies for HIV and influenza virus"
11:20 – 11:50 amLesa Beamer, University of Missouri
"The molecular basis of enzyme dysfunction in phoshoglucomutase 1 deficiency"
11:50 – 12:20 amLynn Howell, The Hospital for Sick Children/University of Toronto
"Microbial Biofilms: Molecular Mechanisms to Therapeutics"
12:20 – 1:20 pmLunch
Session IVProtein folding and Design
Chair: Tom Blundell, University of Cambridge
1:20 – 2:05 pmDavid Eisenberg, University of California, Los Angeles
"Structure-based methods for halting amyloid diseases"
2:05 – 2:40 pmKen Dill, Stony Brook University
"Bayesian integration of knowledge and data into molecular simulations"
2:40 – 3:00 pmRefreshments & Break
3:00 – 3:45 pmDavid Baker, University of Washington
3:45 – 4:20 pmSusan Marqusee, University of California, Berkeley
4:20 – 4:55 pmTobin Sosnick, University of Chicago
"SAXS, IDPs and ultra-fast MD"
5:00 – 6:30 pmPoster Session with Drinks & hors d'oeuvres
6:30 – 7:15 pmEvening Lecture:
Chair: David Baker, University of Washington
Speaker: Tom Blundell, University of Cambridge
7:15 – 8:45 pmDinner
8:45 – 10:00 pmDrinks and Mixing

Tuesday, May 16, 2017
7:00 – 8:30 amBreakfast
Session VCrystallographic Methods
Chair: Wayne Hendrickson, Columbia University
8:30 – 9:10 amJane Richardson, Duke University
"Model-Building Needs Prior Probabilities and Likelihoods"
9:10 – 9:45 amNadia Zatsepin, University of Arizona
9:45 – 10:05 amRefreshments & Break
10:05 – 10:45 amWladek Minor, University of Virginia
10:45 – 11:20 amIsabel Uson, Institute of Molecular Biology, Barcelona
11:20 – 12:00 pmRandy Read, University of Cambridge
"Iduronate sulfatase: structure solution and insights into Hunter syndrome"
12:00 – 1:00 pmLunch
Session VIStructural Biology of Cell Signaling
Chair: Erica Ollmann Saphire, The Scripps Research Institute
1:00 – 1:35 pmDorothee Kern, Brandeis University
1:35 – 2:10 pmAxel Brunger, Stanford University
"Molecular mechanisms of synaptic neurotransmitter release"
2:10 – 2:45 pmYvonne Jones, Oxford University
"The mechanics of semaphorin-plexin cell guidance signalling"
2:45 – 3:05 pmRefreshments & Break
3:05 – 3:40 pmCynthia Wolberger, Johns Hopkins University
"How SAGA reads, writes and erases the histone code"
3:40 – 4:15 pmSharon Campbell, University of North Carolina
4:15 – 4:30 pmRefreshments & Break
Session VIIUnderstanding Enzyme Function
Chair: Susan Marqusee, University of California, Berkeley
4:30 – 5:15 pmIlme Schlichting, Max Planck Institute for Medical Research
5:15 – 5:50 pmAndrzej Joachimiak, Argonne National Laboratory
6:00 – 7:00 pmDrinks & hors d'oeuvres
7:00 – 7:45 pmEvening Lecture:
Chair: Michael Rossmann, Purdue University
Speaker: Tom Steitz, Yale University
"The Structure and Function of the Ribosome Complexes with Various Protein Factors and Antibiotics"
7:45 – 8:45 pmDinner
8:45 - 10:00 pmDrinks and Music

Wednesday, May 17, 2017
Departure

Please contact Shannan Schnedler at sschnedler@newmexicoconsortium.org or Goutam Gupta at gxg@lanl.gov for more information.